AG142015: β-D-GalNAc-Butyl-Carboxylic Acid (Peracetate)

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Description

AG142015: β-D-GalNAc-Butyl-Carboxylic Acid (Peracetate)C19H29NO11 447. 43 A peracetylated D N acetylgalactosamine (GalNAc) ligand equipped with a terminal carboxylic acid through a short butyl spacer, with the sugar hydroxyl groups protected as acetate esters. The peracetate groups increase lipophilicity to facilitate cell membrane permeability. The carboxylic acid can be activated to NHS, sulfo NHS, or pentafluorophenyl (PFP) esters and reacted with amine functionalized platforms or lysine residues on

This probe can be used as a soluble inhibitor or immobilized on plates or sensors to investigate binding

/ β-D-Glc-Ethyl-Thiol / β-Glc-Et-SH

2 / A tri-antennary 6'-sialyl-LacNAc (6SLN3) N-glycan on an Asn core equipped with a biotin tag through a PEG8 spacer

The installed glycan is a galactose residue

/ β-D-Glc-Ethyl-Azide / β-Glc-Et-N3

an enzymatic substrate/acceptor

Vitavel-D-d6

Fmoc-Thr((Ac)4-β-D-Gal)-OH

33 / A β-D-N-acetylglucosamine (GlcNAcβ) ligand equipped with a thiol-functionalized linker through a short ethyl spacer

Radsterin-d6

This is the standard fluorogenic substrate for iduronate-2-sulfatase (IDS)

/ α-L-Rha-Ethyl-Thiol / α-Rha-Et-SH